Sunday, June 05, 2011

Natural Spices Antibacterial Activity On Escherichia coli

This study is the most up-to-date on drug resistant Escherichia coli, from Bangladesh, using lime and natural spices. The conclusion was that: "Natural spices might have anti-bacterial activity against enteric pathogens and could be used for prevention of diarrheal diseases."

"It is interesting to note that even crude extracts of these plants showed good activity against multidrug resistant strains where modern antibiotic therapy has limited effect."

Antibacterial activity of natural spices on multiple drug resistant Escherichia coli isolated from drinking water, Bangladesh
Shahedur Rahman, Anowar Khasru Parvez, Rezuanul Islam, and Mahboob Hossain Khan

Background
Spices traditionally have been used as coloring agents, flavoring agents, preservatives, food additives and medicine in Bangladesh. The present work aimed to find out the antimicrobial activity of natural spices on multi-drug resistant Escherichia coli isolates.

Methods
Anti-bacterial potentials of six crude plant extracts (Allium sativum, Zingiber officinale, Allium cepa, Coriandrum sativum, Piper nigrum and Citrus aurantifolia) were tested against five Escherichia coli isolated from potable water sources at kushtia, Bangladesh.

Results
All the bacterial isolates were susceptible to undiluted lime-juice. None of them were found to be susceptible against the aqueous extracts of garlic, onion, coriander, pepper and ginger alone. However, all the isolates were susceptible when subjected to 1:1:1 aqueous extract of lime, garlic and ginger. The highest inhibition zone was observed with lime (11 mm).

Conclusion
Natural spices might have anti-bacterial activity against enteric pathogens and could be used for prevention of diarrheal diseases. Further evaluation is necessary.

Copyright ©2011 Rahman et al; licensee BioMed Central Ltd.

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